A controversial topic, but a new report concludes that Aspartame and Acesulfame-K can cause cancer due to the carbon isotope 13C.
On April 4, 2022, researchers in France published an extensive study that correlated diet beverage consumption having artificial sweeteners (aspartame and acesulfame-K) with cancer. Do these results raise many issues as to how can components of proteins cause cancer? And how does acesulfame-K (having no amino acids) cause cancer?
Evidence of Stable Isotope 13C Causing All Cancers
Reginald B. Little. Dept of Natural Science, Stillman College
Tuscaloosa, Alabama 35401
In this report, the author concludes that this is evidence that stable uncommon, nonprimordial isotopes (2D, 13C, 15N, 17O, 25Mg, 33S) cause cancer and 13C directly causes cancer.
Aspartame is synthesized from aspartic acid and phenylalanine. And these amino acids are in all proteins. During digestions, proteins are broken down into amino acids. And during digestion of aspartame, phenylalanine and aspartic acids are produced.
So, what is it about aspartic acid and phenylalanine from aspartame that causes cancer, whereas aspartic acid and phenylalanine from other foods do not cause cancer?
Aspartic acid is a nonessential amino acid. Phenylalanine is an essential amino acid, so it is likely the phenylalanine that causes cancer. The author here notes that 13C in phenylalanine and aspartic acids are the reasons aspartame causes cancer.
Acesulfame-K is not synthesized from amino acids, but it is synthesized from precursors having peptide and oligonucleotide-like structures. And acesulfame-K can possibly decompose and interact to cause the decomposition of oligonucleotides for causing cancer.
Acesulfame-K is known to not only disrupts human cells but also bacteria cells .
For instance, experimental data have shown that acesulfame-K accelerates the reproduction of bacterial E. Coli, whereas aspartame decelerates E. Coli reproduction . E Coli is further known and commonly used to enrich amino acids and other biomolecules with stable isotopes of 13C, 15N, and 17O .
Acesulfame-K and Aspartame in diet soda accelerate E. Coli numbers in the guts can cause cancer in the body.
E. Coli is a common bacterium as well as others in the guts and intestines of humans and some animals. Therefore, acesulfame-K and aspartame in diet soda when drank regularly can with carbonates (known to enrich in 13C and 17O under pressures) in beverages accelerate E. Coli numbers in the guts and provide media for E. Coli to produce isotopically enriched amino acids; as the guts act as fermenting reactors for E. Coli to enrich amino acids like glycine, phenylalanine, lysine, leucine, glutamic acid and aspartic acid with 13C, 15N and 17O. The resulting isotopically enriched amino acids like aspartic acid and phenylalanine (from acesulfame-K accelerated E. coli reproduction) then can cause cancer in the body.
Why does aspartame contain elevated amounts of 13C? The aspartame is synthesized by the production of aspartic acid and phenylalanine from bacterial cultures (B. Flavum and C. Glutamicum, respectively) by fermentation processes.
The 13C and 15N are involved in such bacterial fermentation processes as it is known that B. Flavum can enrich aspartic acid with 13C and 15N[4,5]. It is known that C. Glutamicum can enrich phenylalanine with 13C . Therefore, the synthesized aspartame can be enriched with 13C and possibly 15N.
A recent study gives a correlation between chronic aspartame and acesulfame-K ingestion in sodas to cancers of all types. Such study is consistent with the prior theory of RBL of isotopes of 13C enrichment and/or clumping into specific bonds of biomolecules of proteins and nucleic acids for cancer genesis and advancement. Care should be taken for use of bacterial media and algae  for synthesizing drugs and foods in the future . There are currently pressing questions concerning farming and animals and human over-population and the environment and the use of these new technologies for new food sources for less impact on the environment and global warming. Care should be taken to assess and measure subtle stable isotope effects of 2D, 13C, 15N, 17O, 25Mg, and 33S (which might be introduced into humans by such technologies of algae and bacteria) on human health for diseases.
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